GRG Health captured real-world clinical insights from 50 interventional cardiologists and vascular radiologists, analyzing 926 co-registered IVUS–OCT imaging frames across interventional cardiology and radiology settings. The study revealed critical gaps in traditional intravascular imaging, where standalone IVUS or OCT often fail to provide a complete picture of plaque morphology and vessel structure.
Clinicians highlighted the growing need for greater diagnostic clarity, improved plaque characterization, and streamlined workflows during coronary interventions. By combining the depth penetration of IVUS with the high-resolution surface detail of OCT, hybrid imaging enabled clearer interpretation of complex plaques and improved confidence in treatment planning. These insights are helping MedTech innovators refine imaging technology, enhance clinical usability, and advance precision-driven cardiovascular care.
Summary
A leading global MedTech company partnered with GRG Health to evaluate the real-world clinical value of a hybrid intravascular imaging approach that integrates IVUS and OCT into a single, co-registered system, aimed at overcoming long-standing diagnostic limitations in coronary artery disease.
The Challenge?
Fragmented visualization with standalone imaging tools, inconsistent plaque interpretation, workflow inefficiencies, and limited confidence when assessing complex lesions during PCI procedures.
Findings
Using a Clinician-Centric Research Approach, the Study Delivered:
✅ Insights from 50 interventional cardiologists and vascular radiologists across multicenter clinical settings
✅ Analysis of 926 hybrid IVUS–OCT imaging frames to assess diagnostic alignment and clarity
✅ Strong improvement in plaque-type detection agreement (Kappa score: 0.72–0.75)
and many more......
Impact
These findings empowered the client to validate the clinical relevance of hybrid intravascular imaging, strengthen its product positioning, and identify future innovation opportunities.....
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